Enfamil Enspire (Optimum) Infant Formula – Closest Formula to Breast Milk with Lactoferrin, MFGM & DHA | 0‑12 Months
- Enfamil Enspire Optimum Baby Formula Wholesale Supply
- Enfamil Enspire Optimum Infant Milk Powder for Sale
- Premium Enfamil Infant Formula for Newborns and Babies
- Enfamil Enspire Optimum Baby Nutrition Formula Wholesale
Shop Enfamil Enspire Optimum – our closest infant formula ever to breast milk. The first and only leading brand with lactoferrin, a key immune‑supporting protein found in colostrum and breast milk. Features brain‑building MFGM components and expert‑recommended DHA, plus a dual HMO prebiotic blend (2‘‑FL & LnNT) to help nourish your baby’s developing immune system. Our premium, non‑GMO, milk‑based formula contains no artificial growth hormones, colors, or flavors. Available in powder (20.5 oz, 27.4 oz, 30 oz refill) and ready‑to‑feed (2 oz, 8 oz, 32 oz) formats. Breast milk is best for babies. Consult your pediatrician before using infant formula. Contact us for wholesale orders. Delivery by air, land & sea worldwide. Standard & express shipment available.
Product Description
Our Closest Formula to Breast Milk – Premium Science for Your Little One
Enfamil Enspire (now rebranded as Enfamil Optimum) is the premium infant formula from Enfamil, the #1 trusted infant formula brand by pediatricians and parents nationwide. It is a 20 Cal/fl oz, milk‑based, iron‑fortified formula designed to provide complete balanced nutrition for full‑term infants from birth to 12 months. Enspire is formulated to be the brand’s closest formula ever to breast milk – offering unique premium ingredients, including lactoferrin, MFGM components, expert‑recommended DHA, and a dual HMO prebiotic blend.
Lactoferrin – Found in Colostrum & Breast Milk – For Immune & Respiratory Health
Enfamil Enspire is the first and only infant formula in the US containing lactoferrin, a key multifunctional protein naturally present in both colostrum and mature breast milk. Lactoferrin plays a critical role in supporting a baby’s developing immune system, helping to protect against certain pathogens and supporting intestinal development and natural defenses.
MFGM (Milk Fat Globule Membrane) – For Brain Development
Enspire contains MFGM components, derived from whey protein concentrate, a nutrient‑rich membrane found naturally in breast milk. Emerging clinical evidence demonstrates that MFGM helps support healthy cognitive development, and its benefits have been shown to extend through 5 years of age. MFGM is also a source of gangliosides, complex lipids that play an important role in early brain development by helping build neural connections.
Brain‑Building DHA & ARA
Enspire provides DHA and ARA, important omega‑3 and omega‑6 fatty acids clinically shown to support brain and eye development. Enfamil includes the globally recommended amount of DHA(0.32% of total fatty acids) to help nourish your baby’s developing brain, eyes, and nervous system.
Dual HMO Prebiotic Blend (2‘‑FL & LnNT) for Immune Health
Enspire now features an exclusive HuMO6™ immune blend that includes two of the most abundant HMOs (human milk oligosaccharides) naturally found in breast milk – 2’‑FL and LnNT – to help nourish your baby’s developing immune system. HMOs serve as prebiotics that promote the growth of beneficial gut bacteria, supporting your baby’s natural defenses.
Additional Key Nutrients
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Choline & Inositol: Important nutrients found in breast milk that support brain development and cellular function.
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Prebiotic Fiber Blend (PDX & GOS): Helps promote soft, comfortable stools, similar to breastfed infants.
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Dual Prebiotic Fiber Blend (PDX & GOS): Helps promote soft, comfortable stools similar to breastfed infants.
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No Palm Olein Oil (in some formulations): Supports excellent calcium absorption for strong bone development.
Quality & Safety
Enfamil Enspire is non‑GMO, contains no artificial growth hormones, and is free from artificial colors or flavors. It is also gluten‑free and suitable for vegetarian diets (contains milk proteins but no animal‑derived ingredients beyond milk). The formula is made with care in the USA and is designed to be a trusted choice for parents and pediatricians.
✨ Key Features & Benefits
| Feature | Benefit |
|---|---|
| First & Only Formula with Lactoferrin | The only infant formula in the US containing lactoferrin – a key immune‑supporting protein also found in human colostrum and breast milk; supports immune and respiratory health during the critical first weeks of life |
| MFGM Components | Contains Milk Fat Globule Membrane (MFGM) from whey protein concentrate; clinical evidence shows MFGM supports healthy cognitive development with benefits extending to 5 years of age |
| Expert‑Recommended DHA (0.32%) | Clinically proven amount of DHA to help support brain and eye development, patterned after the global average found in mature breast milk |
| Dual HMO Prebiotic Blend (2’‑FL & LnNT) | Two of the most abundant prebiotics naturally found in breast milk; helps support baby’s developing immune system by promoting healthy gut bacteria |
| Exclusive HuMO6™ Immune Blend | A proprietary blend that includes Dual HMOs (2’‑FL & LnNT) plus Vitamins C, E, Selenium, and Zinc – expertly designed to fortify baby’s defenses |
| No Artificial Growth Hormones, Colors or Flavors | Formulated without artificial growth hormones (rbST), artificial colors or flavors, and is non‑GMO – provides peace of mind for clean‑label parents |
| Brain‑Nourishing Choline & Inositol | Key nutrients found in breast milk that support brain development, memory function, and cellular health |
| PDX & GOS Prebiotic Blend | Dual prebiotics that help promote soft, comfortable stools similar to breastfed infants |
| Complete Nutrition for 0‑12 Months | 20 Cal/fl oz, iron‑fortified routine formula providing balanced nutrition for full‑term infants |
| #1 Trusted Infant Formula Brand | Enfamil is the #1 infant formula brand trusted by pediatricians and parents, backed by decades of science and research |
⚙️ Nutritional Information (Powder – Per 5 fl oz prepared / 100 Calories)
| Nutrient | Amount per 5 fl oz | Nutrient | Amount per 5 fl oz |
|---|---|---|---|
| Calories | 100 kcal | Vitamin A | 300 IU |
| Protein | 2.1 g | Vitamin D | 70 IU |
| Total Fat | 5.3 g | Vitamin E | 2 IU |
| Linoleic Acid | 780 mg | Vitamin K | 9 mcg |
| Carbohydrate | 11.1 g | Thiamin (B1) | 80 mcg |
| Water | 133 g | Riboflavin (B2) | 140 mcg |
| Choline | 24 mg | Vitamin B6 | 60 mcg |
| Inositol | 24 mg | Vitamin B12 | 0.3 mcg |
| Calcium | 78 mg | Niacin | 1000 mcg |
| Phosphorus | 43 mg | Folic Acid | 16 mcg |
| Magnesium | 8 mg | Pantothenic Acid | 500 mcg |
| Iron | 1.8 mg | Biotin | 3 mcg |
| Zinc | 1 mg | Vitamin C | 12 mg |
| Sodium | 27 mg | Chloride | 63 mg |
| Potassium | 108 mg | Manganese | 15 mcg |
| Copper | 75 mcg | Iodine | 15 mcg |
| Selenium | 2.5 mcg |
Nutritional values based on standard dilution. Values may vary slightly by format (powder vs liquid). Always refer to the product label for the most accurate information.
Ingredients (Powder): Nonfat Milk, Lactose, Vegetable Oil (contains one or more of the following: Palm Olein Oil, Coconut Oil, Soy Oil, High Oleic Sunflower Oil), Whey Protein Concentrate†, and less than 2%: Lacto‑N‑neotetraose~, 2’‑Fucosyllactose~, Lactoferrin, Mortierella Alpina Oil*, Schizochytrium Sp. Oil**, Calcium Carbonate, Calcium Phosphate, Cupric Sulfate, Ferrous Sulfate, Magnesium Oxide, Manganese Sulfate, Potassium Chloride, Potassium Citrate, Potassium Iodide, Sodium Chloride, Sodium Selenite, Zinc Sulfate, Soy Lecithin, Choline Chloride, Inositol, Ascorbic Acid, Biotin, Calcium Pantothenate, Folic Acid, Niacinamide, Riboflavin, Thiamin Hydrochloride, Vitamin B12, Vitamin B6 Hydrochloride, Vitamin D3, Vitamin K1, Vitamin E Acetate, Vitamin A Palmitate, Taurine, L‑Carnitine.
† A source of MFGM (Milk Fat Globule Membrane composed of proteins and fats) components. ~ A source of HMO (2’‑FL & LnNT human milk oligosaccharides). * A source of Arachidonic Acid (ARA). ** A source of Docosahexaenoic Acid (DHA).
Allergen Information: Contains milk and soy ingredients. Gluten‑free, suitable for vegetarian diets.
📦 Available Packaging Options & Sizes
Powder Formula (Standard Enfamil Enspire / Optimum)
| Format | Container | Size | Approx. Yield | Case Configurations | Best For |
|---|---|---|---|---|---|
| Powder | Reusable Tub | 20.5 oz (581 g) | Makes approx. 130 fl oz | 4‑count case, 6‑count case | Regular home use, cost‑effective daily feeding |
| Powder | Reusable Tub | 27.4 oz (777 g) | Makes approx. 175 fl oz | 4‑count case, 6‑count case | Extended use, larger families |
| Powder | Refill Box (100% Recycled Paperboard) | 30 oz (850 g) | Makes approx. 190 fl oz | 4‑count case | Maximum value, eco‑conscious refill |
Liquid / Ready‑to‑Feed (RTF) – No Mixing Required
IMPORTANT NOTE: The RTF liquid format does NOT contain lactoferrin. For parents who prioritize lactoferrin for immune support, the powder format is recommended.
| Format | Size | Container Type | Preparation | Case Configurations | Best For |
|---|---|---|---|---|---|
| RTF | 2 fl oz (59 mL) | Bottle (with nipple) | No mixing – shake and feed | 24‑pack, 48‑pack | Hospitals, late‑night feedings, travel, single‑serving convenience |
| RTF | 8 fl oz (237 mL) | Bottle | No mixing – shake and feed | 6‑pack carton | Larger single servings, home use |
| RTF | 32 fl oz (946 mL) | Bottle | No mixing – pour required amount | 6‑pack case | Multi‑day supply, easy pouring, home use |
Specialized Variants
| Variant | Description | Best For |
|---|---|---|
| Enfamil Enspire Gentlease | Gentle formula with partially hydrolyzed proteins, 80% less lactose, and a patented prebiotic fiber blend | Fussiness, gas, crying, spit‑up due to sensitive tummies |
📋 How Enspire Optimum Compares – Premium Line-Up
| Nutrient | Enfamil NeuroPro™ | Enfamil Enspire™ Optimum |
|---|---|---|
| Expert‑recommended DHA for brain development | ✔ | ✔ |
| MFGM components from whey protein concentrate | ✔ | ✔ (from whey protein concentrate) |
| Choline & Inositol | ✔ | ✔ |
| Exclusive HuMO6™ immune blend | ✔ (2’‑FL HMO, PDX & GOS) | ✔ (Dual HMOs 2’‑FL & LnNT) |
| Lactoferrin – immune‑supporting protein found in colostrum | – | ✔ (First & Only) |
| Dual HMO blend (2’‑FL & LnNT) | – | ✔ |
| Key Differentiator | Brain‑building DHA + MFGM | Brain‑building MFGM, Dual HMOs & Unique Lactoferrin |
Enspire Optimum is Enfamil’s premium line, formulated with lactoferrin – a distinguishing feature not found in the NeuroPro line.
🍼 Preparation & Usage Instructions
Powder Formula
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Wash hands thoroughly. Clean and sanitize feeding bottles, nipples, and caps.
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Prepare water as directed by your pediatrician. Boil fresh drinking water for 5 minutes and allow it to cool to lukewarm temperature (~37°C / 98°F).
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Pour the exact amount of lukewarm, previously boiled water into the sterilized feeding bottle.
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Add powder: Use ONLY the scoop provided. Add 1 unpacked, level scoop of powder for each 2 fl oz of water.
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Cap and shake well until the powder is completely dissolved.
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Test temperature by placing a few drops on the inside of your wrist – should feel comfortably warm, not hot.
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Feed immediately or refrigerate and use within 24 hours.
Ready‑to‑Feed (RTF)
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Shake the bottle well before opening.
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Check the expiration date – do not use if expired.
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Remove the cap; warm if desired. For 2 fl oz bottles with nipples, attach a sterilized nipple and feed directly.
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Pour the required amount into a clean feeding bottle.
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Feed immediately after opening. Unused formula in opened bottle must be refrigerated and used within 48 hours.
Important Safety Information:
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Once a feeding begins, use within 1 hour and discard any unused formula in the bottle.
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Never use a microwave to warm formula – serious burns can result.
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Store unopened containers in a cool, dry place away from direct sunlight.
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Powdered infant formulas are not sterile and should not be fed to immunocompromised infants without medical supervision.
❄️ Storage & Shelf Life
| Condition | Duration | Instructions |
|---|---|---|
| Unopened (Powder) | 12–18 months (approx.) | Store in a cool, dry place away from direct sunlight and extreme temperatures (ideally below 75°F / 24°C) |
| Opened (Powder) | Up to 1 month | Reseal tightly after each use; store in a cool, dry place – not in the refrigerator |
| Unopened (RTF) | 12–18 months | Store in a cool, dry place away from extreme temperatures |
| Opened (RTF) | 48 hours | Refrigerate immediately after opening (for 8 oz, 32 oz bottles; 2 oz bottles are single‑use). Do not freeze |
DO NOT FREEZE THE FORMULA – Freezing may separate components and compromise nutritional integrity.
❓ Frequently Asked Questions (FAQs)
Q: What makes Enfamil Enspire Optimum different from standard formulas?
A: Enspire is Enfamil‘s premium line, the first and only leading formula containing lactoferrin, a key immune‑supporting protein found in colostrum and breast milk. It also features MFGM for brain development, expert‑recommended DHA, and a dual HMO prebiotic blend.
Q: Is Enfamil Enspire hypoallergenic?
A: No. Enspire is a standard, intact protein milk‑based formula. It is not hypoallergenic and is not suitable for babies with confirmed cow’s milk protein allergy. For CMPA, consult your pediatrician about Nutramigen.
Q: Is Enfamil Enspire suitable for vegans?
A: No. Enspire contains milk and soy ingredients and is not suitable for vegans. It is suitable for vegetarian diets (contains milk proteins but no animal‑derived ingredients beyond milk).
Q: Is Enfamil Enspire halal or kosher certified?
A: Halal and kosher certification vary by region and production batch. Contact us for current certification status in your destination market.
Q: Is Enfamil Enspire gluten‑free?
A: Yes. Enspire does not contain gluten ingredients and is suitable for infants with gluten sensitivity or celiac disease.
Q: How does Enspire compare to Enfamil NeuroPro?
A: NeuroPro focuses on brain development with MFGM & DHA. Enspire adds lactoferrin for immune support, plus a dual HMO blend (2’‑FL & LnNT) – making it the closest formula to breast milk in Enfamil’s lineup.
Q: Does the RTF liquid version contain lactoferrin?
A: No. The RTF liquid format (2 oz, 8 oz, 32 oz) does not contain lactoferrin. For parents who prioritize lactoferrin for immune support, the powder format is recommended.
Q: How should I store opened powder formula?
A: Seal the tub or pouch tightly after each use and store in a cool, dry place (not the refrigerator). Use within 1 month after opening.
Q: Is Enfamil Enspire WIC eligible?
A: In some US states, Enfamil Enspire may be available through WIC (Women, Infants, and Children). Confirm with your local WIC agency.
📜 HS Code & Tariff Classification
For accurate customs documentation and tariff calculation, we provide the correct Harmonized System codes.
| Code | Description |
|---|---|
| HS Code 1901.10 | Preparations for infant use, put up for retail sale |
| Subheading | Milk‑based infant formulas – powders and ready‑to‑feed liquids |
| US HTS Code | 1901.10.00.00 – Preparations suitable for infants or young children, put up for retail sale |
| EU Combined Nomenclature | 1901 10 00 – Preparations for infant use, put up for retail sale |
Export Documents Available:
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Certificate of Analysis (COA) – upon request
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Certificate of Origin – upon request
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Commercial Invoice and Packing List with HS Code specification
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Halal Certificate – upon request (varies by source market)
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MSDS / SDS – available
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Health Certificate – upon request
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ISO / HACCP documentation – available
All documentation provided as required by destination market regulations.
🌍 Global Supply & Delivery Information
We sell only top original quality products at very good and affordable prices. We have warehouses strategically located in the United States, Europe, and the Middle East, ensuring fast and reliable distribution across these regions.
We can ship worldwide via:
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✈️ Air Freight – Express & rapid delivery
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🚚 Land Transportation – Truck delivery within regions
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🚢 Sea Freight – Cost‑effective for bulk orders
Shipping Options Available:
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Standard International Shipping
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Express Worldwide Delivery
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Full Container Load (FCL) Supply
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Bulk Industrial Shipments
We deliver within the United States, Europe, and the Middle East, and we can ship to any destination globally. We support global exports with professional logistics coordination and secure delivery solutions worldwide.
For more inquiries or to place an order (samples, retail packs, wholesale cases, full pallets, or container loads), please contact us.
We deliver by air, land, and sea — internationally. Standard and express shipment options available.











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