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Enfamil Enspire Optimum infant formula – premium milk‑based powder and ready‑to‑feed bottles. Features lactoferrin for immune support, MFGM and DHA for brain development, dual HMOs for immune health. Our closest formula to breast milk for babies 0‑12 months. Purple and gold premium packaging.
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Enfamil Enspire Optimum Infant Formula Wholesale | Premium 0-12 Months Baby Milk Powder Bulk

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Wholesale Enfamil Enspire Optimum infant formula – premium milk-based powder for 0-12 months. Features lactoferrin, MFGM, DHA & dual HMO prebiotics. 20.5 oz tubs & 30 oz refill cases. Non-GMO. Best pricing for retailers & distributors. Get a wholesale quote.

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Enfamil Enspire (Optimum) Infant Formula – Closest Formula to Breast Milk with Lactoferrin, MFGM & DHA | 0‑12 Months

  • Enfamil Enspire Optimum Baby Formula Wholesale Supply
  • Enfamil Enspire Optimum Infant Milk Powder for Sale
  • Premium Enfamil Infant Formula for Newborns and Babies
  • Enfamil Enspire Optimum Baby Nutrition Formula Wholesale

Shop Enfamil Enspire Optimum – our closest infant formula ever to breast milk. The first and only leading brand with lactoferrin, a key immune‑supporting protein found in colostrum and breast milk. Features brain‑building MFGM components and expert‑recommended DHA, plus a dual HMO prebiotic blend (2‘‑FL & LnNT) to help nourish your baby’s developing immune system. Our premium, non‑GMO, milk‑based formula contains no artificial growth hormones, colors, or flavors. Available in powder (20.5 oz, 27.4 oz, 30 oz refill) and ready‑to‑feed (2 oz, 8 oz, 32 oz) formats. Breast milk is best for babies. Consult your pediatrician before using infant formula. Contact us for wholesale orders. Delivery by air, land & sea worldwide. Standard & express shipment available.

Product Description

Our Closest Formula to Breast Milk – Premium Science for Your Little One

Enfamil Enspire (now rebranded as Enfamil Optimum) is the premium infant formula from Enfamil, the #1 trusted infant formula brand by pediatricians and parents nationwide. It is a 20 Cal/fl oz, milk‑based, iron‑fortified formula designed to provide complete balanced nutrition for full‑term infants from birth to 12 months. Enspire is formulated to be the brand’s closest formula ever to breast milk – offering unique premium ingredients, including lactoferrin, MFGM components, expert‑recommended DHA, and a dual HMO prebiotic blend.

Lactoferrin – Found in Colostrum & Breast Milk – For Immune & Respiratory Health
Enfamil Enspire is the first and only infant formula in the US containing lactoferrin, a key multifunctional protein naturally present in both colostrum and mature breast milk. Lactoferrin plays a critical role in supporting a baby’s developing immune system, helping to protect against certain pathogens and supporting intestinal development and natural defenses.

MFGM (Milk Fat Globule Membrane) – For Brain Development
Enspire contains MFGM components, derived from whey protein concentrate, a nutrient‑rich membrane found naturally in breast milk. Emerging clinical evidence demonstrates that MFGM helps support healthy cognitive development, and its benefits have been shown to extend through 5 years of age. MFGM is also a source of gangliosides, complex lipids that play an important role in early brain development by helping build neural connections.

Brain‑Building DHA & ARA
Enspire provides DHA and ARA, important omega‑3 and omega‑6 fatty acids clinically shown to support brain and eye development. Enfamil includes the globally recommended amount of DHA(0.32% of total fatty acids) to help nourish your baby’s developing brain, eyes, and nervous system.

Dual HMO Prebiotic Blend (2‘‑FL & LnNT) for Immune Health
Enspire now features an exclusive HuMO6™ immune blend that includes two of the most abundant HMOs (human milk oligosaccharides) naturally found in breast milk – 2’‑FL and LnNT – to help nourish your baby’s developing immune system. HMOs serve as prebiotics that promote the growth of beneficial gut bacteria, supporting your baby’s natural defenses.

Additional Key Nutrients

  • Choline & Inositol: Important nutrients found in breast milk that support brain development and cellular function.

  • Prebiotic Fiber Blend (PDX & GOS): Helps promote soft, comfortable stools, similar to breastfed infants.

  • Dual Prebiotic Fiber Blend (PDX & GOS): Helps promote soft, comfortable stools similar to breastfed infants.

  • No Palm Olein Oil (in some formulations): Supports excellent calcium absorption for strong bone development.

Quality & Safety

Enfamil Enspire is non‑GMO, contains no artificial growth hormones, and is free from artificial colors or flavors. It is also gluten‑free and suitable for vegetarian diets (contains milk proteins but no animal‑derived ingredients beyond milk). The formula is made with care in the USA and is designed to be a trusted choice for parents and pediatricians.


✨ Key Features & Benefits

Feature Benefit
First & Only Formula with Lactoferrin The only infant formula in the US containing lactoferrin – a key immune‑supporting protein also found in human colostrum and breast milk; supports immune and respiratory health during the critical first weeks of life
MFGM Components Contains Milk Fat Globule Membrane (MFGM) from whey protein concentrate; clinical evidence shows MFGM supports healthy cognitive development with benefits extending to 5 years of age
Expert‑Recommended DHA (0.32%) Clinically proven amount of DHA to help support brain and eye development, patterned after the global average found in mature breast milk
Dual HMO Prebiotic Blend (2’‑FL & LnNT) Two of the most abundant prebiotics naturally found in breast milk; helps support baby’s developing immune system by promoting healthy gut bacteria
Exclusive HuMO6™ Immune Blend A proprietary blend that includes Dual HMOs (2’‑FL & LnNT) plus Vitamins C, E, Selenium, and Zinc – expertly designed to fortify baby’s defenses
No Artificial Growth Hormones, Colors or Flavors Formulated without artificial growth hormones (rbST), artificial colors or flavors, and is non‑GMO – provides peace of mind for clean‑label parents
Brain‑Nourishing Choline & Inositol Key nutrients found in breast milk that support brain development, memory function, and cellular health
PDX & GOS Prebiotic Blend Dual prebiotics that help promote soft, comfortable stools similar to breastfed infants
Complete Nutrition for 0‑12 Months 20 Cal/fl oz, iron‑fortified routine formula providing balanced nutrition for full‑term infants
#1 Trusted Infant Formula Brand Enfamil is the #1 infant formula brand trusted by pediatricians and parents, backed by decades of science and research

⚙️ Nutritional Information (Powder – Per 5 fl oz prepared / 100 Calories)

Nutrient Amount per 5 fl oz Nutrient Amount per 5 fl oz
Calories 100 kcal Vitamin A 300 IU
Protein 2.1 g Vitamin D 70 IU
Total Fat 5.3 g Vitamin E 2 IU
Linoleic Acid 780 mg Vitamin K 9 mcg
Carbohydrate 11.1 g Thiamin (B1) 80 mcg
Water 133 g Riboflavin (B2) 140 mcg
Choline 24 mg Vitamin B6 60 mcg
Inositol 24 mg Vitamin B12 0.3 mcg
Calcium 78 mg Niacin 1000 mcg
Phosphorus 43 mg Folic Acid 16 mcg
Magnesium 8 mg Pantothenic Acid 500 mcg
Iron 1.8 mg Biotin 3 mcg
Zinc 1 mg Vitamin C 12 mg
Sodium 27 mg Chloride 63 mg
Potassium 108 mg Manganese 15 mcg
Copper 75 mcg Iodine 15 mcg
Selenium 2.5 mcg

Nutritional values based on standard dilution. Values may vary slightly by format (powder vs liquid). Always refer to the product label for the most accurate information.

Ingredients (Powder): Nonfat Milk, Lactose, Vegetable Oil (contains one or more of the following: Palm Olein Oil, Coconut Oil, Soy Oil, High Oleic Sunflower Oil), Whey Protein Concentrate†, and less than 2%: Lacto‑N‑neotetraose~, 2’‑Fucosyllactose~, Lactoferrin, Mortierella Alpina Oil*, Schizochytrium Sp. Oil**, Calcium Carbonate, Calcium Phosphate, Cupric Sulfate, Ferrous Sulfate, Magnesium Oxide, Manganese Sulfate, Potassium Chloride, Potassium Citrate, Potassium Iodide, Sodium Chloride, Sodium Selenite, Zinc Sulfate, Soy Lecithin, Choline Chloride, Inositol, Ascorbic Acid, Biotin, Calcium Pantothenate, Folic Acid, Niacinamide, Riboflavin, Thiamin Hydrochloride, Vitamin B12, Vitamin B6 Hydrochloride, Vitamin D3, Vitamin K1, Vitamin E Acetate, Vitamin A Palmitate, Taurine, L‑Carnitine.

† A source of MFGM (Milk Fat Globule Membrane composed of proteins and fats) components. ~ A source of HMO (2’‑FL & LnNT human milk oligosaccharides). * A source of Arachidonic Acid (ARA). ** A source of Docosahexaenoic Acid (DHA).

Allergen Information: Contains milk and soy ingredients. Gluten‑free, suitable for vegetarian diets.


📦 Available Packaging Options & Sizes

Powder Formula (Standard Enfamil Enspire / Optimum)

Format Container Size Approx. Yield Case Configurations Best For
Powder Reusable Tub 20.5 oz (581 g) Makes approx. 130 fl oz 4‑count case, 6‑count case Regular home use, cost‑effective daily feeding
Powder Reusable Tub 27.4 oz (777 g) Makes approx. 175 fl oz 4‑count case, 6‑count case Extended use, larger families
Powder Refill Box (100% Recycled Paperboard) 30 oz (850 g) Makes approx. 190 fl oz 4‑count case Maximum value, eco‑conscious refill

Liquid / Ready‑to‑Feed (RTF) – No Mixing Required

IMPORTANT NOTE: The RTF liquid format does NOT contain lactoferrin. For parents who prioritize lactoferrin for immune support, the powder format is recommended.

Format Size Container Type Preparation Case Configurations Best For
RTF 2 fl oz (59 mL) Bottle (with nipple) No mixing – shake and feed 24‑pack, 48‑pack Hospitals, late‑night feedings, travel, single‑serving convenience
RTF 8 fl oz (237 mL) Bottle No mixing – shake and feed 6‑pack carton Larger single servings, home use
RTF 32 fl oz (946 mL) Bottle No mixing – pour required amount 6‑pack case Multi‑day supply, easy pouring, home use

Specialized Variants

Variant Description Best For
Enfamil Enspire Gentlease Gentle formula with partially hydrolyzed proteins, 80% less lactose, and a patented prebiotic fiber blend Fussiness, gas, crying, spit‑up due to sensitive tummies

📋 How Enspire Optimum Compares – Premium Line-Up

Nutrient Enfamil NeuroPro™ Enfamil Enspire™ Optimum
Expert‑recommended DHA for brain development ✔ ✔
MFGM components from whey protein concentrate ✔ ✔ (from whey protein concentrate)
Choline & Inositol ✔ ✔
Exclusive HuMO6™ immune blend ✔ (2’‑FL HMO, PDX & GOS) ✔ (Dual HMOs 2’‑FL & LnNT)
Lactoferrin – immune‑supporting protein found in colostrum – ✔ (First & Only)
Dual HMO blend (2’‑FL & LnNT) – ✔
Key Differentiator Brain‑building DHA + MFGM Brain‑building MFGM, Dual HMOs & Unique Lactoferrin

Enspire Optimum is Enfamil’s premium line, formulated with lactoferrin – a distinguishing feature not found in the NeuroPro line.


🍼 Preparation & Usage Instructions

Powder Formula

  1. Wash hands thoroughly. Clean and sanitize feeding bottles, nipples, and caps.

  2. Prepare water as directed by your pediatrician. Boil fresh drinking water for 5 minutes and allow it to cool to lukewarm temperature (~37°C / 98°F).

  3. Pour the exact amount of lukewarm, previously boiled water into the sterilized feeding bottle.

  4. Add powder: Use ONLY the scoop provided. Add 1 unpacked, level scoop of powder for each 2 fl oz of water.

  5. Cap and shake well until the powder is completely dissolved.

  6. Test temperature by placing a few drops on the inside of your wrist – should feel comfortably warm, not hot.

  7. Feed immediately or refrigerate and use within 24 hours.

Ready‑to‑Feed (RTF)

  1. Shake the bottle well before opening.

  2. Check the expiration date – do not use if expired.

  3. Remove the cap; warm if desired. For 2 fl oz bottles with nipples, attach a sterilized nipple and feed directly.

  4. Pour the required amount into a clean feeding bottle.

  5. Feed immediately after opening. Unused formula in opened bottle must be refrigerated and used within 48 hours.

Important Safety Information:

  • Once a feeding begins, use within 1 hour and discard any unused formula in the bottle.

  • Never use a microwave to warm formula – serious burns can result.

  • Store unopened containers in a cool, dry place away from direct sunlight.

  • Powdered infant formulas are not sterile and should not be fed to immunocompromised infants without medical supervision.


❄️ Storage & Shelf Life

Condition Duration Instructions
Unopened (Powder) 12–18 months (approx.) Store in a cool, dry place away from direct sunlight and extreme temperatures (ideally below 75°F / 24°C)
Opened (Powder) Up to 1 month Reseal tightly after each use; store in a cool, dry place – not in the refrigerator
Unopened (RTF) 12–18 months Store in a cool, dry place away from extreme temperatures
Opened (RTF) 48 hours Refrigerate immediately after opening (for 8 oz, 32 oz bottles; 2 oz bottles are single‑use). Do not freeze

DO NOT FREEZE THE FORMULA – Freezing may separate components and compromise nutritional integrity.


❓ Frequently Asked Questions (FAQs)

Q: What makes Enfamil Enspire Optimum different from standard formulas?
A: Enspire is Enfamil‘s premium line, the first and only leading formula containing lactoferrin, a key immune‑supporting protein found in colostrum and breast milk. It also features MFGM for brain development, expert‑recommended DHA, and a dual HMO prebiotic blend.

Q: Is Enfamil Enspire hypoallergenic?
A: No. Enspire is a standard, intact protein milk‑based formula. It is not hypoallergenic and is not suitable for babies with confirmed cow’s milk protein allergy. For CMPA, consult your pediatrician about Nutramigen.

Q: Is Enfamil Enspire suitable for vegans?
A: No. Enspire contains milk and soy ingredients and is not suitable for vegans. It is suitable for vegetarian diets (contains milk proteins but no animal‑derived ingredients beyond milk).

Q: Is Enfamil Enspire halal or kosher certified?
A: Halal and kosher certification vary by region and production batch. Contact us for current certification status in your destination market.

Q: Is Enfamil Enspire gluten‑free?
A: Yes. Enspire does not contain gluten ingredients and is suitable for infants with gluten sensitivity or celiac disease.

Q: How does Enspire compare to Enfamil NeuroPro?
A: NeuroPro focuses on brain development with MFGM & DHA. Enspire adds lactoferrin for immune support, plus a dual HMO blend (2’‑FL & LnNT) – making it the closest formula to breast milk in Enfamil’s lineup.

Q: Does the RTF liquid version contain lactoferrin?
A: No. The RTF liquid format (2 oz, 8 oz, 32 oz) does not contain lactoferrin. For parents who prioritize lactoferrin for immune support, the powder format is recommended.

Q: How should I store opened powder formula?
A: Seal the tub or pouch tightly after each use and store in a cool, dry place (not the refrigerator). Use within 1 month after opening.

Q: Is Enfamil Enspire WIC eligible?
A: In some US states, Enfamil Enspire may be available through WIC (Women, Infants, and Children). Confirm with your local WIC agency.


📜 HS Code & Tariff Classification

For accurate customs documentation and tariff calculation, we provide the correct Harmonized System codes.

Code Description
HS Code 1901.10 Preparations for infant use, put up for retail sale
Subheading Milk‑based infant formulas – powders and ready‑to‑feed liquids
US HTS Code 1901.10.00.00 – Preparations suitable for infants or young children, put up for retail sale
EU Combined Nomenclature 1901 10 00 – Preparations for infant use, put up for retail sale

Export Documents Available:

  • Certificate of Analysis (COA) – upon request

  • Certificate of Origin – upon request

  • Commercial Invoice and Packing List with HS Code specification

  • Halal Certificate – upon request (varies by source market)

  • MSDS / SDS – available

  • Health Certificate – upon request

  • ISO / HACCP documentation – available

All documentation provided as required by destination market regulations.


🌍 Global Supply & Delivery Information

We sell only top original quality products at very good and affordable prices. We have warehouses strategically located in the United States, Europe, and the Middle East, ensuring fast and reliable distribution across these regions.

We can ship worldwide via:

  • ✈️ Air Freight – Express & rapid delivery

  • 🚚 Land Transportation – Truck delivery within regions

  • 🚢 Sea Freight – Cost‑effective for bulk orders

Shipping Options Available:

  • Standard International Shipping

  • Express Worldwide Delivery

  • Full Container Load (FCL) Supply

  • Bulk Industrial Shipments

We deliver within the United States, Europe, and the Middle East, and we can ship to any destination globally. We support global exports with professional logistics coordination and secure delivery solutions worldwide.

 

For more inquiries or to place an order (samples, retail packs, wholesale cases, full pallets, or container loads), please contact us.
We deliver by air, land, and sea — internationally. Standard and express shipment options available.

 

 

 

 

 

 

 

 

Amazon.com: Enfamil Optimum (Enspire), Our Closest Formula to Breast Milk, Immune-Supporting Lactoferrin and Brain-Supporting DHA Baby Formula, 30 Oz Refill : Everything Else Enfamil Enspire Gentlease Infant Formula 19.5 oz Tub - Betty Mills

 

Amazon.com: Enfamil Enspire Gentlease Infant Formula with Immune-Supporting Lactoferrin, Brain Building DHA, 5 Nutrient Benefits in 1 Formula, Eases Gas, Fussiness, Spit-up, Crying in 24 hours, Refill Box, 29 Oz : Baby

 

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